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Table 1 Association of USP7 expression with clinicopathological parameters in 100 HCC patients

From: Ubiquitin-specific protease 7 is a drug-able target that promotes hepatocellular carcinoma and chemoresistance

Parameters

Total

USP7 expression

P value

High

Low

Sex

0.362

 Male

82

39

43

 

 Female

18

10

8

 

Age (years)

0.487

  < 50

42

20

22

 

  ≥ 50

58

29

29

 

AFP (ng/ml)

0.556

  < 400

67

33

34

 

  ≥ 400

33

16

17

 

Tumor size (cm)

0.018*

  < 5

40

14

26

 

  ≥ 5

60

35

25

 

Tumor number

0.247

 Single

82

42

40

 

 Multiple

18

7

11

 

Tumor differentiation

0.007*

 I-II

75

31

44

 

 III

25

18

7

 

Portal vein tumor thrombus

0.149

 Yes

25

15

10

 

 No

75

34

41

 

TNM stage

0.004*

 I-II

34

10

24

 

 III-IV

66

39

27

 

HBV infection

0.548

 Yes

76

37

39

 

 No

24

12

12

 

Liver cirrhosis

0.025*

 Yes

65

37

28

 

 No

35

12

23

 
  1. HCC hepatocellular carcinoma, AFP α-fetoprotein, HBV hepatitis B virus, TNM topography, lymph node, metastasis. Statistical analyses were performed by the Pearson χ2 test
  2. * P < 0.05 was considered significant