Fig. 2
From: Construction of a novel gene-based model for prognosis prediction of clear cell renal cell carcinoma
Data processing, screening of the DEGs. a A PCA plot of the data showing no batch effect in the TCGA KIRC dataset. Red nodes represent the normal cluster while blue nodes represent the tumor cluster. b Heatmap of top 20 DEGs in ccRCC. c Volcano plot of differentially expressed genes in ccRCC when compared with normal tissue. Red nodes represent the significantly up-regulated genes with logFC > 4 and p < 0.05. Green nodes represent the significantly down-regulated genes with logFC < -4 and p < 0.05. PCA, principal component analysis; TCGA, The Cancer Genome Atlas; DEGs, differentially expressed genes; ccRCC, clear cell renal cell carcinoma