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Fig. 5 | Cancer Cell International

Fig. 5

From: Demonstration of anti-tumour bystander killing with prodrug-preloaded suicide gene-engineered tumour cells: a potential improvement for cancer therapeutics

Fig. 5

Pre-treated mouse mesothelioma AE17-STK induce bystander killing on: AE17 (a) and AB1 cells (b). The indicated ratios of AE-STK cells were mixed and plated at an initial cell density of 5 × 104/well in 96-well plates. In one set the AE-STK cells were GCV pre-loaded (pre-treated) by incubation with 30 μM of GCV for 16 h. In the other set (treated) there was no GCV pre-loading, but 30 μM GCV was added to the culture for the duration of the experiment. These cultures were incubated for 5 days and % cell survival was assessed by the MTT assay. Error bars represent standard error of the mean. Representative of three similar experiments

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