Fig. 5

a The landscape of immune cell infiltrates sorted by increasing purity in TCGA-GBM RNA-seq dataset. Immune cell infiltrates were estimated by ssGSEA algorithm. b The correlation between the proportion of immune cell infiltrates and survival (upper panel) or purity estimates (lower panel) in TCGA-GBM or CGGA RNA-seq cohort. Purity values in CGGA cohort were inferred by ESTIMATE method. c Correlation plot showing Spearman’s Rho between cell types in TCGA-GBM. d Scatter plot of correlation of tumor purity and CYT (a geometric mean of GZMA and PRF1; y-axis in log2 scale). e Correlation between immune checkpoints gene expression (TCGA RNA-seq dataset) and tumor purity. Pearson’s correlation coefficients (r) are stated