Fig. 3
From: Knockdown of lncRNA SNHG16 suppresses multiple myeloma cell proliferation by sponging miR-342-3p
Knockdown of SNHG16 promoted MM cell apoptosis and regulation apoptosis and cell cycle-related proteins expression. a Represented image of apoptosis. Cell apoptosis of RPMI-8226 and NCI-H929 cells were assessed by flow cytometry at 48 h after transfected. b The bar graph represents the total apoptotic rate. The total apoptosis includes early apoptotic rate (LR) and late apoptotic rate (UR). ***P < 0.001. c The CCND1 expression was measured by qRT-PCR at 48 h after transfected. d, e The expression of Cleaved-Caspase-3/9, Cyclin D1, PI3K, p-AKT, AKT, Foxo3a, Bax, Bcl-2, and total Caspase-3/9 proteins in RPMI-8226 and NCI-H929 cells were measured by western blot at 48 h after transfected