Fig. 2
From: Hsa_circ_0011385 accelerates the progression of thyroid cancer by targeting miR-361-3p
Hsa_circ_0011385 knockdown inhibited thyroid cancer cell proliferation and promoted cell cycle arrest. a BCPAP cells were transfected with hsa_circ_0011385 siRNAs, and the expression level of hsa_circ_0011385 was analyzed by qRT-PCR assay (**P < 0.01 vs. NC group). b Western blot assay was carried out to evaluate Bax, caspase-3, TIMP, MMP2 and MMP9 expression levels in BCPAP cells after hsa_circ_0011385 knockdown. GAPDH was used as a reference. c CCK-8 assay was performed to evaluate cell viability in BCPAP cells transfected with hsa_circ_0011385 siRNAs (**P < 0.01 vs. NC group). d Proliferation ability was assessed by CFSE assay in BCPAP cells after hsa_circ_0011385 knockdown (**P < 0.01 vs. NC group). e Cell cycle distribution was confirmed by flow cytometry in BCPAP cells after hsa_circ_0011385 knockdown (*P < 0.05 vs. NC group)