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Fig. 5 | Cancer Cell International

Fig. 5

From: Downregulation of Siah1 promotes colorectal cancer cell proliferation and migration by regulating AKT and YAP ubiquitylation and proteasome degradation

Fig. 5

Silencing of Siah1 promotes migration and invasion of CRC cells. a Depletion of Siah1 in SW480 and HCT116 accelerates the migratory speed of CRC cells, as detected by wound-healing assays. Scale bar: 50 μm. b Silencing of Siah1 in SW480 and HCT116 increases the migratory number of CRC cells, as determined by Transwell chamber invasion assays. Each bar represents the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001. Scale bar: 50 μm

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Cancer Cell International

ISSN: 1475-2867

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