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Table 2 Subgroup analyses of OS and CSS

From: The prognostic value of De Ritis (AST/ALT) ratio in patients after surgery for urothelial carcinoma: a systematic review and meta-analysis

Outcome

Variable

Number of studies

Model

HR (95% CI)

I2 (%)

P value of heterogeneity

OS

All

7

Fixed

1.97 (1.70–2.28)

0.0

0.563

No. of patients

≤ 500

3

Fixed

2.30 (1.66–3.20)

0.0

0.670

> 500

4

Fixed

1.90 (1.61–2.23)

0.0

0.396

Cutoff

≤ 1.3

5

Fixed

1.88 (1.57–2.26)

4.4

0.382

> 1.3

2

Fixed

2.13 (1.67–2.71)

0.0

0.850

Disease

BC

3

Fixed

1.80 (1.43–2.27)

47.3

0.150

UTUC

4

Fixed

2.08 (1.73–2.51)

0.0

0.988

CSS

All

4

Fixed

2.61 (2.06–3.31)

5.1

0.367

No. of patients

≤ 500

3

Fixed

2.73 (1.82–4.10)

35.9

0.210

> 500

4

Fixed

2.34 (1.93–2.83)

30.0

0.232

Cutoff

≤ 1.3

5

Fixed

2.30 (1.84–2.88)

46.5

0.113

> 1.3

2

Fixed

2.57 (1.95–3.39)

0.0

0.956

Disease

BC

3

Random

2.71 (1.38–5.31)

65.2

0.056

UTUC

3

Fixed

2.59 (2.08–3.21)

0.0

0.839

  1. OS overall survival, CSS cancer-specific survival, BC bladder cancer, UTUC upper tract urothelial carcinoma
  2. – Not available