Fig. 4
From: MicroRNA-4316 inhibits gastric cancer proliferation and migration via directly targeting VEGF-A
MiR-4316-reduced VEGF-A and suppressed proliferation of GC cells. a qRT-PCR confirmed the VEGF-A expression after knocked down with si-VEGF-A or N.C in SGC-7901 and BGC-823. b By Western blot, the quantitative level of VEGF-A and c-Met protein expression was decreased after transfection and co-transfection in SGC-7901 and BGC-823 with si-VEGF-A, miR-4316-mimic + si-VEGF-A or miR-4316-inhibitor plus si-VEGF-A or N.C. c, d The proliferation in SGC-7901 and BGC-823 was detected by CCK-8 and colony formation assay after transfection and co-transfection with si-VEGF-A, miR-4316-mimic plus si-VEGF-A, miR-4316-inhibitor plus si-VEGF-A or N.C. *P < 0.05, **P < 0.001, ***P < 0.001 and ****P < 0.0001