Skip to main content

Table 2 Results of subgroup and meta-regression analyses

From: Integrated characterization and validation of the prognostic significance of microRNA-200s in colorectal cancer

Subgroup

Studies

HR (95% CI)

P-value

Heterogeneity (I2) (%)

Pheterogeneity

Meta-regression (P-value)

Sample source

P = 0.196

 Blood

9

0.89 (0.76–1.05)

P = 0.161

68.5

P = 0.001

 

 Tissue

21

1.16 (1.08–1.26)

P < 0.001

64.4

P < 0.001

 

Sample size

P = 0.124

 Large (> median)

16

1.06(1.01–1.12)

P = 0.036

40.5

P = 0.047

 

 Small (< median)

14

1.17 (0.94–1.46)

P = 0.159

82.1

P < 0.001

 

Ethnicity

P = 0.136

 Asian

3

0.69 (0.23–2.01)

P = 0.491

81.3

P = 0.005

 

 Europeans

10

0.98 (0.87–1.10)

P = 0.707

72.1

P < 0.001

 

 Americans

17

1.19 (1.08–1.30)

P < 0.001

67.1

P < 0.001

 

miR-200s classification

P = 0.656

 miR-200a

10

1.13 (1.01–1.26)

P = 0.027

69.6

P = 0.001

 

 miR-200b

9

1.14 (0.97–1.33)

P = 0.113

72.3

P < 0.001

 

 miR-200c

11

1.00 (0.85–1.17)

P = 0.973

74.0

P < 0.001

Â