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Table 2 Results of subgroup and meta-regression analyses

From: Integrated characterization and validation of the prognostic significance of microRNA-200s in colorectal cancer

SubgroupStudiesHR (95% CI)P-valueHeterogeneity (I2) (%)PheterogeneityMeta-regression (P-value)
Sample sourceP = 0.196
 Blood90.89 (0.76–1.05)P = 0.16168.5P = 0.001 
 Tissue211.16 (1.08–1.26)P < 0.00164.4P < 0.001 
Sample sizeP = 0.124
 Large (> median)161.06(1.01–1.12)P = 0.03640.5P = 0.047 
 Small (< median)141.17 (0.94–1.46)P = 0.15982.1P < 0.001 
EthnicityP = 0.136
 Asian30.69 (0.23–2.01)P = 0.49181.3P = 0.005 
 Europeans100.98 (0.87–1.10)P = 0.70772.1P < 0.001 
 Americans171.19 (1.08–1.30)P < 0.00167.1P < 0.001 
miR-200s classificationP = 0.656
 miR-200a101.13 (1.01–1.26)P = 0.02769.6P = 0.001 
 miR-200b91.14 (0.97–1.33)P = 0.11372.3P < 0.001 
 miR-200c111.00 (0.85–1.17)P = 0.97374.0P < 0.001