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Fig. 5 | Cancer Cell International

Fig. 5

From: Hsa_circ_0137008 suppresses the malignant phenotype in colorectal cancer by acting as a microRNA-338-5p sponge

Fig. 5

Upregulation of hsa_circ_0137008 attenuated the effect of miR-338-5p on CRC cell proliferation. a The expression levels of miR-338-5p were detected in SW480 and HCT116 cells transfected with miR-NC, miR-338-5p mimic or pcDNA3.1-circ_0137008. b, c The viability of SW480 and HCT116 cells was examined by CCK-8 assay. d The colony formation abilities of SW480 and HCT116 cells was determined by colony formation assay. e The expression of Ki67 and PCNA was determined using western blot. f, g Results of quantitative analysis of the Ki67 and PCNA protein levels were shown. *P < 0.05

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