Breast cancer pathogenesis is linked to the intra-tumoral estrogen sulfotransferase (hSULT1E1) expressions regulated by cellular redox dependent Nrf-2/NFκβ interplay

Table 3 Statistical analysis of Pearson’s correlations amongst different oxidative-stress parameters and SULT1E1 expressions in three different diseases conditions in the tumor/surrounding tissues

Grade	S_SULT1E1	T_NPSH	T_MDA	T_SULT1E1	PD_NPSH	PD_MDA
II	All parameters of S and T correlated at p < 0.05 to p < 0.001 level
III
S_NPSH
r	0.761	− 0.655	− 0.435	0.807	− 0.865*	0.456
P	0.079	0.158	0.389	0.052	0.026	0.363
S_MDA
r	− 0.257	0.948**	0.925**	− 0.417	0.816*	− 0.17
P	0.623	0.004	0.008	0.41	0.048	0.747
T_NPSH
r	− 0.152	1	0.798	− 0.322	0.877*	− 0.362
P	0.774		0.057	0.533	0.022	0.481
IV
S_NPSH
r	− 0.893	− 0.281	0.997*	− 0.878	− 0.637	− 0.292
P	0.298	0.819	0.05	0.317	0.56	0.811
S_MDA
r	1.000**	0.683	− 0.855	0.569	0.916	0.691
P	0.001	0.522	0.347	0.615	0.263	0.514
T_NPSH
r	0.683	1	− 0.205	− 0.212	0.919	1.000**
P	0.521		0.868	0.864	0.258	0.007

A significant correlation between SULT1E1 expression and MDA and NPSH were noticed in all disease grades
Italic values indicate level of significance p < 0.05
*Correlation is significant at the 0.05 level (2-tailed)