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Table 1 Clinicopathological characteristics of participants in TCGA cohort

From: A four-DNA methylation signature as a novel prognostic biomarker for survival of patients with gastric cancer

Characteristics

Groups

Patients

Total (N = 368)

Training dataset (N = 184)

Validation dataset (N = 184)

Sample (n, %)

Sample (n, %)

Sample (n,%)

Age at diagnosis

Median (IQR)

67.00 (58.00, 73.00)

67.50 (58.00, 73.00)

66.00 (58.00, 73.00)

Sex

Female

123 (33.4)

62 (33.7)

61 (33.2)

Male

245 (66.6)

122 (66.3)

123 (66.8)

Live status

Living

226 (61.4)

113 (61.4)

113 (61.4)

Death

142 (38.6)

71 (38.6)

71 (38.6)

Pathologic T

T1–2

93 (25.3)

44 (23.9)

49 (26.6)

T3–4

275 (74.7)

140 (76.1)

135 (73.4)

Pathologic N

N0

113 (30.7)

58 (31.5)

55 (29.9)

N1–3

255 (69.3)

126 (68.5)

129 (70.1)

Pathologic M

M0

334 (90.8)

165 (89.7)

169 (91.8)

M1–3

34 (9.2)

19 (10.3)

15 (8.2)

Pathological stage

I–II

166 (45.1)

86 (46.7)

80 (43.5)

III–IV

202 (54.9)

98 (53.3)

104 (56.5)

Histologic grade

G1–2

139 (37.8)

70 (38.0)

69 (37.5)

G3–4

229 (62.2)

114 (62.0)

115 (62.5)

Histological type

Diffuse

78 (21.2)

39 (21.2)

39 (21.2)

Intestinal

171 (46.5)

86 (46.7)

85 (46.2)

NOS

119 (32.3)

59 (32.1)

60 (32.6)

Anatomic subdivision

Antrum

134 (36.4)

66 (35.9)

68 (37.0)

Cardia

49 (13.3)

27 (14.7)

22 (12.0)

Fundus

134 (36.4)

66 (35.9)

68 (37.0)

GEJ

42 (11.4)

20 (10.9)

22 (12.0)

NOS

9 (2.4)

5 (2.7)

4 (2.2)