Skip to main content
Fig. 1 | Cancer Cell International

Fig. 1

From: MYC-regulated lncRNA NEAT1 promotes B cell proliferation and lymphomagenesis via the miR-34b-5p-GLI1 pathway in diffuse large B-cell lymphoma

Fig. 1

LncRNAs NEAT1 and GLI1 were upregulated while miR-34b-5p was downregulated in DLBCL tissues and cell lines. a The levels of NEAT1, GLI1 and miR-34b-5p were detected by RT-qPCR in tissues from DLBCL patients with MYC rearrangement (n = 8), patients without MYC rearrangement (n = 22) or healthy donors (n = 30). **P < 0.01 vs. normal, T-test. b The levels of NEAT1, GLI1 and miR-34b-5p were measured by RT-qPCR in the DLBCL cell lines OCI-Ly1, OCI-Ly8, OCI-Ly10, SUDHL-4 and in normal B cells. *P < 0.05 and **P < 0.01 vs. normal B cells, T-test. c Immunoblotting and quantification of GLI1 (and β-actin as loading control) in DLBCL cell lines OCI-Ly1, OCI-Ly8, OCI-Ly10, SUDHL-4 and in normal B cells. *P < 0.05 and ***P < 0.001 vs. normal B cells, T-test

Back to article page