Table 1 Laboratory parameters in AFP-negative patients and healthy controls
Characteristics | Healthy controls (N = 199) | AFP-negative CH (N = 184) | AFP-negative LC (N = 151) | AFP-NHCC (N = 180) | pa | pb | pc | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Gender (male/female) | 169/30 |  | 145/39 |  | 115/36 |  | 163/17 |  | 0.097 | 0.002 | < 0.001 |
Age (years) | 50.00 | 42.00–56.00 | 39.50 | 32.00–48.75 | 46.00 | 37.00–54.00 | 50.00 | 43.25–58.00 | 0.212 | < 0.001 | < 0.001 |
WBC (× 109/L) | 6.10 | 5.38–6.87 | 6.21 | 5.24–7.19 | 5.76 | 3.98–7.39 | 6.00 | 5.06–7.47 | 0.837 | 0.793 | 0.027 |
Hb (g/L) | 149.50 | 140.30–156.00 | 139.35 | 127.00–147.55 | 115.10 | 92.00–137.40 | 136.60 | 126.25–145.48 | < 0.001 | 0.233 | < 0.001 |
TBIL (μmol/L) | 11.0 | 8.40–13.50 | 12.60 | 9.03–17.78 | 13.70 | 9.20–31.00 | 11.90 | 8.98–16.28 | 0.012 | 0.356 | 0.001 |
AST (U/L) | 21.00 | 18.00–24.00 | 28.50 | 21.00–46.00 | 32.00 | 22.00–49.00 | 31.00 | 25.00–42.00 | < 0.001 | 0.060 | 0.975 |
ALT (U/L) | 20.00 | 16.00–25.00 | 32.00 | 20.25–77.75 | 27.00 | 18.00–45.00 | 33.00 | 25.00–46.75 | < 0.001 | 0.667 | 0.007 |
PLT (× 109/L) | 241.00 | 207.40–280.30 | 203.00 | 169.27–246.38 | 166.70 | 96.80–244.20 | 169.75 | 129.12–214.42 | < 0.001 | < 0.001 | 0.547 |
Fib (g/L) | 2.84 | 2.54–3.21 | 2.69 | 2.24–3.23 | 2.30 | 1.78–3.03 | 3.21 | 2.73–3.95 | < 0.001 | < 0.001 | < 0.001 |
PA (mg/L) | 305.10 | 280.00–338.30 | 204.45 | 166.92–244.12 | 165.30 | 111.50–218.80 | 195.00 | 165.18–235.55 | < 0.001 | 0.031 | < 0.001 |
GGT (U/L) | 29.00 | 22.00–37.00 | 34.55 | 23.18–67.80 | 36.00 | 22.00–55.00 | 45.00 | 33.25–91.50 | < 0.001 | < 0.001 | < 0.001 |
FPR | 9.34 | 7.94–10.57 | 13.65 | 11.42–15.35 | 14.26 | 10.97–17.57 | 16.25 | 12.89–21.20 | < 0.001 | < 0.001 | < 0.001 |
GPR | 0.12 | 0.08–0.16 | 0.18 | 0.11–0.36 | 0.23 | 0.13–0.39 | 0.31 | 0.18–0.56 | < 0.001 | < 0.001 | < 0.001 |