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Table 2 Relationship between relative expression of miR-21 and PEG3 and clinicopathological features in patients with glioma

From: M2 bone marrow-derived macrophage-derived exosomes shuffle microRNA-21 to accelerate immune escape of glioma by modulating PEG3

Clinicopathological data

n

miR-21 expression

p

PEG3 expression

p

Low expression group (n = 35)

High expression group (n = 36)

Low expression group (n = 36)

High expression group (n = 35)

Age (year)

   

0.188

  

0.736

< 50

44

19

25

 

23

21

 

≥ 50

27

16

11

 

13

14

 

Gender

   

0.559

  

0.288

Male

39

18

21

 

22

17

 

Female

32

17

15

 

14

18

 

Tumor location

   

0.196

  

0.168

Forehead

22

13

9

 

10

12

 

Crown

19

6

13

 

12

7

 

Pulvinar

16

7

9

 

10

6

 

Temple

14

9

5

 

4

10

 

WHO classification

   

0.005

  

0.001

I + II

41

26

15

 

14

27

 

III + IV

30

9

21

 

22

8

 

KPS score

   

0.281

  

0.120

< 70

33

14

19

 

20

13

 

≥ 70

38

21

17

 

16

22

 

Tumor size (cm)

   

0.024

  

0.006

< 5

37

23

14

 

13

24

 

≥ 5

34

12

22

 

23

11

 
  1. The data in this table were enumeration data, which were tested by Chi square test
  2. miR-21 microRNA-21, PEG3 paternally expressed gene 3, WHO World Health Organization, KPS Karnofsky performance status
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Cancer Cell International

ISSN: 1475-2867

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