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Fig. 3 | Cancer Cell International

Fig. 3

From: RETRACTED ARTICLE: Inhibition of ZEB1-AS1 confers cisplatin sensitivity in breast cancer by promoting microRNA-129-5p-dependent ZEB1 downregulation

Fig. 3

miR-129-5p overexpression or ZEB1-AS1 silencing decreases the expression profiles of ZEB1-AS1, Bcl-2, MDR1 and ZEB1 but increases that of miR-129-5p. a Relative expression of related genes in ZEB1-AS1/miR-129-5p/ZEB1 axis in MCF-7 cell line determined by RT-qPCR; b relative expression of related genes in ZEB1-AS1/miR-129-5p/ZEB1 axis in MD-MB-231 cell line determined by RT-qPCR; c protein expression level of related genes in ZEB1-AS1/miR-129-5p/ZEB1 axis in MCF-7 cell line measured by western blot; d protein expression level of related genes in ZEB1-AS1/miR-129-5p/ZEB1 axis in MD-MB-231 cell line measured by western blot; * indicates p < 0.05 vs. the control group; ZEB1-AS1 zinc finger E-box-binding homeobox 1-antisense 1, ZEB1 zinc finger E-box-binding homeobox 1, miR-129-5p microRNA-129-5p, Bcl-2 B cell lymphoma/lewkmia-2, MDR1 multidrug resistance, RT-qPCR reverse transcription quantitative polymerase chain reaction

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