Fig. 7
From: MiR-26a/miR-26b represses tongue squamous cell carcinoma progression by targeting PAK1
Upregulation of PAK1 weakened promotion of apoptosis induced by miR-26a and miR-26b in TSCC cells. SCC4 and Cal27 cells were transfected with miR-NC, miR-26a/miR-26b mimic, miR-26a/miR-26b mimic + pcDNA Vector or miR-26a/miR-26b mimic + pcDNA-PAK1. a–d Flow cytometry assay for the apoptotic rate (Q2 + Q4) of transfected SCC4 and Cal27 cells, as determined by ANOVA analysis followed by Tukey test. e–h Western blot assay for the protein levels of Bax and Bcl-2 in treated SCC4 and Cal27 cells, as determined by ANOVA analysis followed by Tukey test. **P < 0.01, ***P < 0.001