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Fig. 2 | Cancer Cell International

Fig. 2

From: Deciphering molecular mechanisms underlying chemoresistance in relapsed AML patients: towards precision medicine overcoming drug resistance

Fig. 2

Expression levels of nucleoside influx transporters and nucleoside salvage pathway enzymes. RNA was purified from AML patient specimens using tri reagent as described in the Methods section. Gene expression levels were determined using quantitative RT-PCR. a, b Comparison of the expression levels at diagnosis in patients with good response to chemotherapy (GR1-5) and in relapsed patients (P1-D and P2-D). The results are presented as fold over GUSB which served as an internal control. c, d Comparison of the expression levels at the diagnosis and relapse stages in the relapsed patients. Results shown are normalized to GUSB which served as an internal control, and presented as fold over the expression levels of P1-D

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