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Table 5 The effect of genetic variants in IL-1B/IL-1RN on the susceptibility of nasopharyngeal carcinoma and thyroid carcinoma

From: Effects of in IL-1B/IL-1RN variants on the susceptibility to head and neck cancer in a chinese Han population

Gene SNP ID Model Genotype Control Nasopharyngeal carcinoma Thyroid carcinoma
Case OR (95% CI) p Case OR (95% CI) p
IL-1B rs1143643 Allele C 564 87 1   371 1  
  T 512 72 1.02 (0.72–1.43) 0.924 425 1.26 (1.05–1.52) 0.013*
Genotype CC 146 20 1   82 1  
  CT 272 38 1.03 (0.51–2.07) 0.946 207 1.61 (1.1–2.34) 0.014*
  TT 120 17 1.06 (0.59–1.91) 0.841 109 1.34 (0.97–1.86) 0.080
Dominant CC 146 20 1   82 1  
  CT-TT 392 55 1.05 (0.60–1.83) 0.863 316 1.42 (1.04–1.94) 0.027*
Recessive CC-CT 418 58 1   289 1  
  TT 120 17 0.99 (0.55–1.77) 0.961 109 1.31 (0.97–1.78) 0.078
Log-additive     1.01 (0.72–1.44) 0.936   1.27 (1.05–1.53) 0.015*
  1. SNP single nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval
  2. p values were calculated by logistic regression analysis with adjustments for age and gender
  3. *p < 0.05 respects the data is statistically significant