|
Variable
|
COS3, %
|
CCSS3, %
|
|---|
|
Years since diagnosis
|
Years since diagnosis
|
|---|
|
Basline
|
1y
|
2y
|
3y
|
4y
|
5y
|
Basline
|
1y
|
2y
|
3y
|
4y
|
5y
|
|---|
|
Overall
|
71.8
|
72.9
|
76.5
|
77.9
|
79.6
|
79.3
|
77.1
|
78.1
|
81.3
|
82.7
|
84.9
|
85.8
|
|
Age (year)
|
|
< 65
|
75.8
|
76.3
|
78.9
|
82.1
|
84.1
|
83.3
|
79.0
|
79.8
|
81.7
|
84.8
|
87.6
|
88.6
|
|
≥ 65
|
65.5
|
66.9
|
71.9
|
69.5
|
70.3
|
70.5
|
73.9
|
75.0
|
80.6
|
78.4
|
79.1
|
79.6
|
|
d (< 65 vs. ≥ 65)
|
0.23
|
0.21
|
0.17
|
0.31
|
0.35
|
0.31
|
0.12
|
0.12
|
0.03
|
0.16
|
0.24
|
0.26
|
|
Sex
|
|
Male
|
69.5
|
73.6
|
76.2
|
76.2
|
76.8
|
75.5
|
75.1
|
79.5
|
81.7
|
81.7
|
82.1
|
83.9
|
|
Female
|
73.8
|
72.3
|
76.7
|
79.3
|
81.9
|
82.3
|
78.7
|
76.9
|
85.0
|
83.4
|
87.2
|
87.3
|
|
d (male vs. female)
|
− 0.10
|
0.03
|
− 0.01
|
− 0.08
|
− 0.13
|
− 0.17
|
− 0.09
|
0.06
|
− 0.08
|
− 0.04
|
− 0.14
|
− 0.10
|
|
Marital status
|
|
Married
|
73.3
|
76.6
|
79.8
|
79.6
|
78.9
|
79.6
| | | | | | |
|
Unmarried
|
71.9
|
70.9
|
74.8
|
81.0
|
82.8
|
79.4
| | | | | | |
|
Unknown
|
67.8
|
64.1
|
68.6
|
70.7
|
79.8
|
78.0
| | | | | | |
|
d (married vs. unmarried)
|
0.03
|
0.13
|
0.12
|
− 0.03
|
− 0.09
|
0.0
| | | | | | |
|
d (married vs. unknown)
|
0.12
|
0.28
|
0.26
|
0.21
|
− 0.02
|
− 0.02
|
0.11
|
0.11
|
0.24
|
0.17
|
− 0.11
|
− 0.07
|
|
FNCLCC grade
|
|
I
|
90.5
|
87.7
|
87.1
|
89.1
|
85.4
|
90.0
|
93.0
|
93.4
|
92.9
|
94.4
|
94.4
|
98.2
|
|
II
|
75.6
|
69.9
|
65.7
|
71.8
|
83.5
|
94.4
|
82.8
|
74.7
|
69.4
|
76.0
|
88.4
|
100.0
|
|
III
|
53.8
|
58.5
|
66.2
|
68.0
|
71.5
|
78.9
|
61.2
|
65.8
|
72.0
|
72.0
|
74.1
|
81.7
|
|
Unknown
|
72.7
|
73.6
|
77.4
|
77.8
|
79.7
|
79.1
|
77.6
|
78.2
|
81.7
|
82.6
|
85.3
|
85.6
|
|
d (I vs. II)
|
0.33
|
0.40
|
0.50
|
0.42
|
0.05
|
− 0.11
|
0.24
|
0.46
|
0.60
|
0.49
|
0.17
|
− 0.05
|
|
d (I vs. III)
|
0.82
|
0.65
|
0.50
|
0.51
|
0.35
|
0.27
|
0.76
|
0.67
|
0.54
|
0.59
|
0.56
|
0.47
|
|
d (I vs. Unknown)
|
0.40
|
0.32
|
0.23
|
0.27
|
0.14
|
0.66
|
0.37
|
0.37
|
0.29
|
0.31
|
0.25
|
0.36
|
|
Size (cm)
|
|
< 5
|
84.8
|
80.9
|
87.0
|
87.3
|
75.1
|
71.8
|
90.9
|
86.4
|
91.7
|
89.1
|
75.1
|
71.8
|
|
5–10
|
75.4
|
75.9
|
79.0
|
82.1
|
88.1
|
90.4
|
80.6
|
80.8
|
82.9
|
85.5
|
89.5
|
92.4
|
|
10–15
|
72.5
|
69.0
|
75.4
|
78.3
|
80.6
|
80.6
|
78.6
|
75.5
|
80.5
|
82.9
|
86.4
|
87.3
|
|
≥ 15
|
69.0
|
72.6
|
75.6
|
76.6
|
77.2
|
76.7
|
74
|
77.3
|
80.5
|
81.5
|
83.5
|
84.6
|
|
Unknown
|
74.1
|
66.9
|
67.5
|
61.0
|
66.9
|
57.2
|
79.5
|
73.8
|
74.6
|
74.1
|
83.7
|
74.8
|
|
d (< 5 vs. 5–10)
|
0.21
|
0.11
|
0.19
|
0.13
|
− 0.33
|
− 0.45
|
0.25
|
0.14
|
0.23
|
0.09
|
− 0.40
|
− 0.59
|
|
d (< 5 vs. 10–15)
|
0.27
|
0.26
|
0.28
|
0.22
|
0.14
|
− 0.21
|
0.29
|
0.27
|
0.29
|
0.16
|
− 0.31
|
− 0.44
|
|
d (< 5 vs. ≥ 15)
|
0.35
|
0.18
|
0.27
|
0.26
|
0.05
|
− 0.12
|
0.40
|
0.22
|
0.29
|
0.20
|
− 0.23
|
− 0.37
|
|
d (< 5 vs. Unknown)
|
0.24
|
0.32
|
0.46
|
0.63
|
0.20
|
0.89
|
0.27
|
0.30
|
0.44
|
0.40
|
− 0.24
|
− 0.09
|
|
Multifocality
|
|
No
|
69.7
|
70.4
|
74.7
|
76.7
|
79.6
|
79.1
|
73.6
|
74.2
|
77.8
|
79.5
|
87.1
|
83.1
|
|
Yes
|
84.1
|
85.6
|
84.6
|
82.9
|
79.6
|
79.7
|
97.5
|
98.4
|
97.5
|
95.9
|
94.7
|
96.0
|
|
d (No vs. Yes)
|
− 0.32
|
− 0.34
|
− 0.24
|
− 0.15
|
0
|
− 0.01
|
− 0.57
|
− 0.59
|
− 0.51
|
− 0.43
|
− 0.21
|
− 0.37
|
|
Histology
|
|
SFT
|
86.7
|
86.7
|
88.9
|
88.9
|
76.2
|
68.6
|
86.7
|
86.7
|
88.9
|
88.9
|
76.2
|
68.6
|
|
MFHC
|
41.7
|
56.0
|
66.7
|
80.0
|
64.3
|
50.0
|
49.2
|
62.0
|
70.6
|
80
|
71.4
|
64.8
|
|
MPNST
|
62.3
|
63.5
|
71.4
|
55.6
|
66.7
|
66.7
|
76.2
|
76.2
|
85.7
|
100.0
|
100.0
|
100.0
|
|
LMS
|
70.2
|
67.4
|
71.6
|
73.4
|
79.6
|
84.1
|
75.6
|
72.6
|
75.6
|
75.7
|
81.6
|
85.7
|
|
DD lipo
|
63.6
|
65.8
|
66.6
|
66.7
|
66.5
|
68.2
|
68.7
|
70.7
|
72.4
|
72.3
|
74.2
|
76.9
|
|
WD lipo
|
90.4
|
88.0
|
88.5
|
86.3
|
88.2
|
86.3
|
95.6
|
93.8
|
94.2
|
91.7
|
92.4
|
91.7
|
|
Other
|
67.9
|
71.3
|
77.5
|
81.0
|
82.2
|
80.1
|
72.7
|
76.1
|
81.5
|
86.4
|
88.9
|
88.7
|
|
d (SFT vs. MFHC)
|
1.00
|
0.68
|
0.53
|
0.22
|
0.30
|
0.45
|
0.89
|
0.60
|
0.47
|
0.23
|
0.13
|
0.11
|
|
d (SFT vs. MPNST)
|
0.54
|
0.52
|
0.42
|
0.81
|
0.24
|
0.05
|
0.25
|
0.26
|
0.08
|
− 0.29
|
− 0.66
|
− 0.90
|
|
d (SFT vs. LMS)
|
0.37
|
0.43
|
0.41
|
0.38
|
− 0.09
|
− 0.38
|
0.26
|
0.34
|
0.34
|
0.35
|
− 0.15
|
− 0.49
|
|
d (SFT vs. DD lipo)
|
0.51
|
0.46
|
0.53
|
0.54
|
0.24
|
0.01
|
0.43
|
0.39
|
0.42
|
0.44
|
0.06
|
− 0.24
|
|
d (SFT vs. WD lipo)
|
− 0.08
|
− 0.03
|
0.01
|
0.06
|
− 0.30
|
− 0.43
|
− 0.21
|
− 0.17
|
− 0.14
|
− 0.07
|
− 0.45
|
− 0.66
|
|
d (SFT vs. Other)
|
0.42
|
0.34
|
0.27
|
0.19
|
− 0.15
|
− 0.28
|
0.33
|
0.26
|
0.19
|
0.07
|
− 0.35
|
− 0.57
|
|
Chemotherapy
|
|
No
|
74.9
|
75.9
|
78.8
|
79.8
|
81.3
|
80.2
|
80.6
|
81.3
|
83.8
|
84.5
|
86.5
|
86.7
|
|
Yes
|
53.8
|
53.9
|
60.6
|
63.2
|
66.2
|
71.2
|
56.2
|
58.0
|
64.1
|
68.6
|
72.2
|
77.7
|
|
d (No vs. Yes)
|
0.47
|
0.49
|
0.43
|
0.40
|
0.38
|
0.22
|
0.58
|
0.57
|
0.51
|
0.42
|
0.40
|
0.26
|
- SFT solitary fibrous tumor, MFHC Malignant fibrous histiocytoma, MPNST malignant peripheral nerve sheath tumor, LMS leiomyosarcoma, DD lipo dedifferentiated liposarcoma, WD lipo well-differentiated liposarcoma, FNCLCC French National Federation of the Centers for the Fight Against Cancer, API Asian/Pacific Islander, COS3 3-year conditional overall survival, CCSS3 3-year conditional cancer-specific survival, y year, d standardized difference
