Skip to main content
Fig. 6 | Cancer Cell International

Fig. 6

From: CircTP63 promotes hepatocellular carcinoma progression by sponging miR-155-5p and upregulating ZBTB18

Fig. 6

CircTP63 promotes HCC progression by regulation of the miR-155-5p/ZBTB18 axis. a, b mRNA and protein expression levels of ZBTB18 in SK-hep1 and SNU-387 cells transfected with si-NC, si-circTP63#1, si-circTP63#1 + miR-155-5p inhibitor or si-circTP63#1 + pcDNA3.1-ZBTB18 was evaluated using qRT-PCR and western blotting assays. c Pearson correlation analysis between circTP63 and ZBTB18 expressions in 90 pairs of HCC tissues. d, e CCK8 and colony formation assays were used to assess the proliferation of SK-hep1 and SNU-387 cells transfected with si-NC, si-circTP63#1, si-circTP63#1 + miR-155-5p inhibitor or si-circTP63#1 + pcDNA3.1-ZBTB18. f, g Transwell assays were used to assess the migration and invasion of SK-hep1 and SNU-387 cells transfected with si-NC, si-circTP63#1, si-circTP63#1 + miR-155-5p inhibitor or si-circTP63#1 + pcDNA3.1-ZBTB18. Data are representative of three independent experiments and shown as mean ± SD., **P < 0.01, compared to the si-NC group; ## P < 0.01, compared to the si-circTP63#1 group

Back to article page