Fig. 1
From: Prognostic values, ceRNA network, and immune regulation function of SDPR in KRAS-mutant lung cancer
SDPR as a potential target for the treatment of KRAS-mutant lung cancer. a Transcriptional expression profiling in murine normal lung and tumor tissues with KRAS mutation based on GEO dataset (GSE18784, GSE49200). b The differentially expressed genes (DEGs) between murine normal and KRAS-mutant lung tumor tissues (normal vs tumor = 18 vs 34; normal vs tumor = 19 vs 31, respectively). The gene structure and phylogenetic conservative analysis of SDPR. c Chromosome location of SDPR is marked in red. d Alignment analysis results of SDPR protein among Homo sapiens and other species is shown, and different sequences are marked in red. e Phylogenetic tree of Homo sapiens CAV and CAVIN family proteins including SDPR (highlighted in red frame). The tree was drawn to scale based on the above family proteins sequence (Uniprotdatabase), with branch lengths in the same units as those of the evolutionary distances used to infer the phylogenetic tree. The evolutionary distances were computed and visualized using MEGA software and iTOL website (https://itol.embl.de/)