Fig. 5From: Potential diagnostic and prognostic value and regulatory relationship of long noncoding RNA CCAT1 and miR-130a-3p in clear cell renal cell carcinomaKnockdown of CCAT1 inhibits the proliferation and invasion and induces the apoptosis of ccRCC cells. a expression level of miR-130a-3p in different groups. b cell proliferation effect was assessed using CCK-8. c transwell assay. Representative microscopic images of cells that migrated through the transwell in the migration assay. Scale bar = 100 µm. ×200 magnification. d apoptosis effect was assessed using flow cytometry. The apoptosis ratio was calculated as follows: apoptosis ratio (%) = (the percentage of early apoptotic cells) + (the percentage of late apoptotic cells). The percentage of cells is presented in the area of respective quadrant profiles. Comparisons between groups were performed using one-way ANOVA. *P < 0.05Back to article page