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Fig. 5 | Cancer Cell International

Fig. 5

From: Three novel circRNAs upregulated in tissue and plasma from hepatocellular carcinoma patients and their regulatory network

Fig. 5

Identification of 19 hub genes from the interaction network. a A PPI network of the 95 candidate genes consists of 67 nodes and 358 edges. The node size varies from small to large according to the number of neighbored genes. b A subnetwork consists of 19 nodes and 166 edges extracted from (a) with the MCODE clustering algorithm. PPI protein-protein interaction. c Volcano plot showing the 19 hub genes in TCGA-LIHC (left) and GSE14520 (right) datasets

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