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Table 2 Basic information of 19 significantly up-regulated hub genes in TCGA-LIHC and GSE14520-GPL3921

From: Three novel circRNAs upregulated in tissue and plasma from hepatocellular carcinoma patients and their regulatory network

Hub genes

MCODE Score

Log2(Fold Change)

Log-rank P value of overall survival

TCGA-LIHC

GSE14520

TCGA-LIHC

GSE14520

NUSAP1

16.50292398

1.60

2.37

0.0081**

0.1060

CCNA2

16.50292398

1.08

1.28

0.0012**

0.0514

MCM6

16.50292398

1.01

2.02

0.0003***

0.0124*

CCNB1

16.50292398

1.00

2.49

0.0001***

0.0021**

CDC20

16.50292398

1.58

1.90

< 0.0001****

0.0459*

BUB1B

16.50292398

4.74

1.71

0.0032**

0.0666

NDC80

16.50292398

4.46

1.31

0.0025**

0.0444*

ZWINT

16.50292398

1.14

2.43

< 0.0001****

0.0056**

ASPM

16.50292398

1.02

3.01

0.0172*

0.0014**

CENPU

15.58169935

1.81

1.96

0.0020**

0.0113*

FANCI

15.58169935

2.21

1.19

0.0132*

0.1117

GMNN

15.58169935

1.57

2.13

0.3349

0.0195*

HELLS

15.58169935

2.58

1.05

0.0204*

0.0554

MCM3

15.58169935

1.95

1.48

0.0261*

0.0333*

MCM5

15.58169935

2.10

1.38

0.0039**

0.0015**

ECT2

15.58169935

4.73

2.03

0.0050**

0.0254*

CDC7

15.58169935

3.75

1.09

0.0002***

0.0357*

RRM1

15.58169935

1.24

1.12

0.0294*

0.0613

DLGAP5

15.58169935

3.32

1.31

0.0003***

0.0320*