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Table 6 Survival analysis for 12 significantly up-regulated hub genes in TCGA-LIHC

From: Three novel circRNAs upregulated in tissue and plasma from hepatocellular carcinoma patients and their regulatory network

Hubgenes DFI DSS PFI
HR(95 %CI) Log-rank P value HR(95 %CI) Log-rank P value HR(95 %CI) Log-rank P value
MCM6 1.923(1.358–2.724) < 0.0001**** 1.901(1.217–2.971) 0.0040** 1.865(1.386–2.510) < 0.0001****
CCNB1 1.847(1.323–2.578) 0.0002*** 2.189(1.404–3.412) 0.0005*** 1.947(1.447–2.619) < 0.0001****
CDC20 1.614(1.144–2.278) 0.0038** 3.028(1.936–4.736) < 0.0001**** 1.809(1.345–2.434) < 0.0001****
NDC80 1.497(1.077–2.081) 0.0155* 1.786(1.145–2.786) 0.0098** 1.501(1.118–2.015) 0.0061**
ZWINT 2.076(1.466–2.938) < 0.0001**** 2.170(1.390–3.389) 0.0006*** 1.899(1.377–2.499) < 0.0001****
ASPM 1.419(1.022–1.972) 0.0360* 1.794(1.135–2.767) 0.0104* 1.432(1.068–1.920) 0.0158*
CENPU 1.497(1.077–2.081) 0.0155* 1.786(1.145–2.786) 0.0098** 1.501(1.118–2.015) 0.0061**
MCM3 1.615(1.160–2.248) 0.0039** 1.734(1.109–2.711) 0.0131* 1.627(1.210–2.186) 0.0010**
MCM5 1.372(0.986–1.908) 0.0576 1.623(1.040–2.532) 0.0305* 1.446(1.076–1.942) 0.0128*
ECT2 1.488(1.070–2.070) 0.0168* 2.084(1.338–3.245) 0.0013** 1.564(1.166–2.098) 0.0026**
CDC7 1.255(0.902–1.745) 0.1726 2.151(1.376–3.364) 0.0006*** 1.453(1.073–1.967) 0.0128*
DLGAP5 1.484(1.067–2.064) 0.0177* 2.262(1.452–3.525) 0.0004*** 1.671(1.245–2.243) 0.0005***
  1. HR hazard ratio, DFI disease-free interval, DSS disease specific survival, PFI progression free interval