Fig. 1From: Monoclonal antibodies and chimeric antigen receptor (CAR) T cells in the treatment of colorectal cancerThe structure of different types of mAbs. All the components of mouse mAbs are derived from mice. In chimeric mAbs, the variable regions of a mice Ab is fused with the constant regions of a human Ab. In humanized mAbs, only the hypervariable regions (CDRs) of the mAb are originated from mice. All the components of human mAbs are derived from humansBack to article page