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Fig. 5 | Cancer Cell International

Fig. 5

From: Hsa_circ_0010235 functions as an oncogenic drive in non-small cell lung cancer by modulating miR-433-3p/TIPRL axis

Fig. 5

MiR-433-3p acted as a suppressor in NSCLC development. H1299 and A549 cells were transfected with miR-NC or miR-433-3p. a QRT-PCR assay for the relative expression of miR-433-3p in transfected cells. b, c CCK-8 assay for the cell viability of transfected cells. d Colony formation assay for the colony formation ability of transfected cells. e Flow cytometry for the apoptotic rate of transfected cells. f, g Flow cytometry for the cell cycle distribution in G0/G1, S and G2/M phases of transfected cells. h Western blot assay for the protein levels of LC3-I, LC3-II and p62 in transfected cells. i, j Transwell assay for the migration and invasion of transfected cells. k Wound healing assay for the migration capacity of transfected cells. *P < 0.05

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