Fig. 3
From: Postponing tumor onset and tumor progression can be achieved by alteration of local tumor immunity
Differentially expressed genes in tumor progression and metastasis. a Venn diagram of DEGs. Genes involved in the antigen processing and presentation (GO: 19882), antigen processing and presentation of peptide antigen (GO: 48002) and the antigen processing and presentation of peptide antigen via MHC class I (GO: 02474) were collected as immune-related genes in this study. All DEGs in each tumor stage were used in depicting the Venn diagram. b–d Hierarchical clustering of immune-related DEGs. The expression pattern for the immune-related DEGs from adenoma b, late carcinoma of the mammary gland (c), and lung metastasis (d) are illustrated by the heatmap. Expression levels are depicted by the color bar beside the heatmap