Fig. 4

MiR-142-5p exerted tumor-suppressive effect in gliomas. a miR NC, miR-142-5p mimics, inhibitor NC and miR-142-5p inhibitors were transfected into U87 and U251 cells. The expression of miR-142-5p was detected by qRT-PCR 48 h after transfection. (n = 3). b After 48 h of transfection, CCK-8 assay was used to detect cell proliferation after the inhibition or overexpression of miR-142-5p. (n = 3). c Transwell assay was used to detect cell migration and invasion after inhibition or overexpression of miR-142-5p (magnification: ×400). (n = 3). Inhibitor NC: Inhibitor negative control, miR-142-5p in: miR-142-5p inhibitor, miR NC: miR negative control, miR-142-5p: miR-142-5p mimics, **P < 0.01 and ***P < 0.001