Fig. 5

The effects of circ_0000020 on glioma cells was partly dependent on miR-142-5p. U87 cells were transfected with si-circ_0000020, miR-142-5p inhibitors, or si-circ_0000020 + miR-142-5p inhibitors; U251 cells were transfected with circ_0000020 overexpression plasmid, miR-142-5p mimics, or circ_0000020 overexpression plasmid + miR-142-5p mimics. a, b The proliferation, migration and invasion of were detected by CCK-8 assay (a) and Transwell assay (b), respectively. (n = 3). Control: negative control, miR-142-5p in: miR-142-5p inhibitor, si-circ_0000020: siRNA against circ_0000020, miR-142-5p: miR-142-5p mimics, circ_0000020: pcDNA-circ_0000020, Error bars represented the mean ± SD of at least three independent experiments; *P < 0.05, **P < 0.01 and ***P < 0.001