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Fig. 7 | Cancer Cell International

Fig. 7

From: Circ_0000020 elevates the expression of PIK3CA and facilitates the malignant phenotypes of glioma cells via targeting miR-142-5p

Fig. 7

Knockdown of circ_0000020 inhibited glioma growth in vivo. a, b U87 cells transfected with si-circ_0000020 or si-NC were used for tumor xenograft assay. The tumor volume and weight in vivo was measured. c HE staining was used for evaluating lung metastasis of the mice. d, e The expressions of circ_0000020 and miR-142-5p in tumor tissues of the mice were examined by qRT-PCR. f The expression of PIK3CA in tumor tissues of the mice was examined by Western blot. si-NC: siRNA normal control, si-circ_0000020: siRNA against circ_0000020, GAPDH: glyceraldehyde-3-phosphate dehydrogenase, Error bars represented the mean ± SD of at least three independent experiments; ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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