Fig. 4
From: LncRNA ACTA2-AS1 suppress colon adenocarcinoma progression by sponging miR-4428 upregulation BCL2L11
miR-4428 directly interacted with BCL2L11. a The putative binding sites between BCL2L11 and miR-4428. b Relative BCL2L11 expression in cells co-transfected with wt and mut BCL2L11 and miR-4428 mimics in SW480 and HT29 cells using luciferase reporter assay. c Relative BCL2L11 mRNA expression in SW480 and HT29 cells transfected with miR-4428 mimics and miR-4428 inhibitor. d Relative BCL2L11 protein expression in SW480 and HT29 cells transfected with miR-4428 mimics and miR-4428 inhibitor. e Apoptosis-related protein Bax and Bcl-2 expression in SW480 and HT29 cells transfected with sh-ACTA2-AS1 and OE ACTA2-AS1. GAPDH was used as a loading control. f Relative BCL2L11 expression in 82 pairs of COAD tissues and their adjacent normal tissues. g Spearman’s rank order correlation between miR-4428 and BCL2L1. *p < 0.05; **p < 0.01