Skip to main content

Table 5 Univariate binary logistic regression analysis for the lymph node metastatic risk

From: Cofilin-1, LIMK1 and SSH1 are differentially expressed in locally advanced colorectal cancer and according to consensus molecular subtypes

Parameter n Odds ratio (OR) 95% confidence interval P value
Gender
 Female 26 0.485 0.151–1.558 0.224
 Male 23 1   
Age at surgery (years)
 < 65 23 0.727 0.228–2.316 0.590
 ≥ 65 26 1   
Tumor size (cm3)
 < 33 25 0.788 0.249–2.490 0.684
 ≥ 33 24    
Localization
 Colon 27 1.203 0.377–3.835 0.755
 Colon sigmoideum/rectum 22 1   
Tumor type
 Adenocarcinoma 40 0.241 0.052–1.118 0.069
 Mucinous 9 1   
Tumor grade
 Moderately-well 46 0.293 0.025–3.479 0.331
 Poor 3 1   
T grade
 T1/2 15 0.063 0.007–0.538 0.011
 T3/4 34 1   
Lymphovascular invasion
 Absent 36 0.171 0.043–0.683 0.012
 Present 13 1   
Perineural invasion
 Absent 38 0.264 0.065–1.076 0.063
  Present 11 1   
Cofilin-1 IHC score
  Low 23 0.238 0.068–0.836 0.025
 High 26 1   
SSH1 IHC score
  Low 23 0.238 0.068–0.836 0.025
  High 26 1   
LIMK1 IHC score
 Low 24 0.900 0.285–2.843 0.858
 High 25 1