Fig. 4
From: Cisplatin loaded multiwalled carbon nanotubes reverse drug resistance in NSCLC by inhibiting EMT
Pt-MWNTS induced cell apoptosis of A549 & A549/DDP. a Representative flow cytometry data for the detection of apoptosis in A549 and A549/DDP cells treated with PBS, MWNTS, cisplatin (Pt) and Pt-MWNTS at 30 μg/ml. b Quantification of the percent of apoptotic cells in each treatment group. c Representative western blot showing the protein levels of apoptosis markers Bax, Bid, Bim, Bcl-2, Caspase-3, Caspase-9 and PAPR-1. β-actin served as loading control. A549/DDP cells were treated under different drug concentration for 48 h. d Quantification of the relative amount of each protein detected by western blot. Data represented mean \(\pm\) SD of three independent experments. (n = 3, *P < 0.05, **P < 0.01, ***P < 0.001 vs Control.)