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Fig. 2 | Cancer Cell International

Fig. 2

From: LncRNA MEG8 promotes NSCLC progression by modulating the miR-15a-5p-miR-15b-5p/PSAT1 axis

Fig. 2

The depletion of lncRNA MEG8 reduces NSCLC cell proliferation, migration and invasion in vitro. ae The A549 and H1299 cells were infected with the lentiviral plasmids carrying MEG8 shRNA (shMEG8) or corresponding control shRNA (shNC). a The expression levels of lncRNA MEG8 were tested by qPCR assays in the cells. b The cell viability was measured by CCK-8 assays in the cells. c The cell proliferation was tested by EdU assays in the cells, in which the pink represented EdU and the blue represented nuclear stained by Hoechst. d The cell migration and invasion were examined by transwell assays in the cells. e The cell apoptosis was measure by flow cytometry analysis in the cells, in which the x-axis represented the Annexin V-FITC and the y-axis represented the propidium iodide (PI). Data are presented as mean ± SD. Statistic significant differences were indicated: *P < 0.05, **P < 0.01

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