From: Adeno‐associated virus (AAV)-based gene therapy for glioblastoma
Factor | AAV serotype | Delivered approach | References |
---|---|---|---|
HSV-tk | – | Intratumoral injection | [62] |
IFN-β | AAV2 | Intratumoral injection | [63] |
sVEGFR1/R2 | – | Intratumoral injection | [25] |
Anti-VEGF | AAVrh.10 | Intratumoral injection | [64] |
TFPI-2 | – | Intratumoral injection | [65] |
hTERTC27 | – | Intratumoral injection | [66] |
Decorin | AAV2 | Intratumoral injection | [61] |
TRAIL | AAVrh.8 | Intratumoral injection | [67] |
ADP | AAV2 | Intratumoral injection | [55] |
MiR-7 | – | Intratumoral injection | [68] |
IFN-β | – | ICVinjection | [29] |
sTRAIL | AAV9 | Systematic injection | [78] |
IFN-β | AAV9 | Systematic injection | [80] |