Fig. 7
From: LiCl induces apoptosis via CHOP/NOXA/Mcl-1 axis in human choroidal melanoma cells
The NOXA/Mcl-1 axis contributes to LiCl-induced apoptosis in vivo. a b The nude mice were sacrificed for western blotting and immunohistochemical (IHC) analysis. Western blotting was performed to assess the protein levels of NOXA and Mcl-1 in xenograft tumours. c The tumour sections were stained for IHC analysis using antibodies against Ki67 and representative IHC images are shown in figure. Magnification: × 40. Corresponding scale bars are depicted in the lower right corner of each image. Scale bars = 100 μm. d The percentages of Ki67-positive cells in the normal saline and LiCl groups. All data are presented as the mean ± S.D. *P < 0.05, **P < 0.01