Fig. 4

M2 macrophages-derived exosomal miR-501-3p facilitates LC cell proliferation and suppresses apoptosis. a miR-501-3p expression in A549 and SPC-A1 cells detected using RT-qPCR; b proliferation of A549 and SPC-A1 cells detected by CCK-8 assay; c colony formation ability of A549 and SPC-A1 cells detected by colony formation assay; d apoptosis of A549 and SPC-A1 cells detected by flow cytometry; N = 3; *P < 0.05 vs the mimic NC group, ^#P < 0.05 vs the M2-Exos + inhibitor NC group; the measurement data were expressed as mean ± standard deviation, one-way ANOVA was used for comparisons among multiple groups and Tukey’s post hoc test was used for pairwise comparisons after one-way ANOVA