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Fig. 2 | Cancer Cell International

Fig. 2

From: Re-expression of miR-200s in claudin‐low mammary tumor cells alters cell shape and reduces proliferation and invasion potentially through modulating other miRNAs and SUZ12 regulated genes

Fig. 2

Cell morphology. Crystal violet staining of murine (a–e) and human (f–j) mammary tumor cells. Mammary tumor cells with a luminal phenotype (a, f) display a more rounded/cuboidal morphology while mammary tumor cells with a claudin-low phenotype (b, g) display a more spindle-like morphology. Re-expression of the miR-200b/200a/429 cluster in RJ423 cells (e) and the miR-200c/141 cluster in MDA-MB-231 cells (i) reverted these cells to a more luminal morphology. Scale bars are 25 µm

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Cancer Cell International

ISSN: 1475-2867

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