Table 1 Top 10 upregulated and downregulated miRNAs as determined by miRNA-seq
Upregulated miRNAs | log2FC | p-value | Downregulated miRNAs | log2FC | p-value |
|---|---|---|---|---|---|
MDA-231c141 vs. MDA-231EV | |||||
hsa-miR-200c-3p | 7.1 | 0 | hsa-miR-335-3p | − 12.2 | 0 |
hsa-miR-129-5p | 3.8 | 3.1 × 10−65 | hsa-miR-452-5p | − 9.5 | 0 |
hsa-miR-141-3p | 5.3 | 1.5 × 10 −58 | hsa-miR-34c-5p | − 3.9 | 1.4 × 10−136 |
hsa-miR-139-5p | 2.2 | 5.4 × 10−50 | hsa-miR-34a-5p | − 3.8 | 1.1 × 10−67 |
hsa-miR-1301-3p | 2.6 | 3.4 × 10−47 | hsa-miR-210-3p | − 2.8 | 4.1 × 10−63 |
hsa-miR-30a-5p | 1.6 | 6.0 × 10−46 | hsa-miR-335-5p | − 7.9 | 1.1 × 10−59 |
hsa-miR-194-5p | 2.2 | 1.3 × 10−45 | hsa-miR-27b-5p | − 2.4 | 9.0 × 10−58 |
hsa-miR-192-5p | 2.3 | 7.8 × 10−43 | hsa-miR-23b-3p | − 1.7 | 2.6 × 10−43 |
hsa-miR-455-5p | 1.8 | 1.3 × 10−40 | hsa-miR-34b-3p | − 4.4 | 1.4 × 10−41 |
hsa-miR-7156-5p | 5.2 | 2.1 × 10−35 | hsa-miR-10399-3p | − 2.5 | 2.1 × 10−39 |
MDA-231ba429 vs. MD-231EV | |||||
hsa-miR-200b-3p | 2.9 | 3.7 × 10 −71 | hsa-miR-27b-3p | − 1.7 | 7.6 × 10−59 |
hsa-miR-200a-3p | 3.2 | 4.1 × 10 −48 | hsa-miR-1269b | − 8.7 | 6.2 × 10−40 |
hsa-miR-200a-5p | 3.2 | 2.3 × 10 −32 | hsa-miR-3681-5p | − 3.9 | 3.1 × 10−39 |
hsa-miR-200b-5p | 2.9 | 1.1 × 10 −26 | hsa-miR-34a-5p | − 3.5 | 5.3 × 10−39 |
hsa-miR-30c-2-3p | 1.1 | 2.0 × 10−17 | hsa-miR-27b-5p | − 2.1 | 1.2 × 10−34 |
hsa-miR-708-5p | 4.8 | 9.1 × 10−17 | hsa-miR-125b-2-3p | − 6.1 | 4.6 × 10−33 |
hsa-miR-218-5p | 1.2 | 4.2 × 10−14 | hsa-miR-196a-5p | − 3.5 | 1.4 × 10−19 |
hsa-miR-449c-5p | 1.8 | 1.6 × 10−13 | hsa-miR-95-3p | − 2.5 | 4.5 × 10−18 |
hsa-miR-3074-5p | 1.6 | 1.1 × 10−11 | hsa-miR-516a-5p | − 4.0 | 1.3 × 10−17 |
hsa-mir-429 | 1.7 | 3.6 × 10 −11 | hsa-miR-23b-3p | − 1.4 | 9.9 × 10−17 |
RJ423c141 vs. RJ423EV | |||||
mmu-miR-200c-3p | 5.9 | 3.9 × 10 −51 | mmu-miR-365-5p | − 8.3 | 3.4 × 10−13 |
mmu-miR-615-3p | 8.0 | 5.0 × 10−43 | mmu-miR-132-3p | − 3.1 | 6.5 × 10−12 |
mmu-miR-146b-5p | 2.5 | 4.9 × 10−13 | mmu-miR-212-5p | − 4.0 | 7.3 × 10−10 |
mmu-miR-99a-5p | 2.1 | 4.1 × 10−12 | mmu-miR-1983 | − 1.9 | 6.9 × 10−9 |
mmu-miR-378c | 2.6 | 7.6 × 10−12 | mmu-miR-6540-5p | − 8.0 | 1.2 × 10−7 |
mmu-miR-378d | 2.4 | 7.6 × 10−12 | mmu-miR-212-3p | − 4.7 | 4.2 × 10−6 |
mmu-miR-378a-3p | 2.3 | 2.1 × 10−11 | mmu-miR-210-3p | − 1.3 | 5.4 × 10−5 |
mmu-miR-125b-2-3p | 1.9 | 7.1 × 10−9 | mmu-miR-124-3p | − 3.0 | 2.3 × 10−4 |
mmu-miR-141-5p | 5.9 | 2.5 × 10 −8 | mmu-miR-582-3p | − 2.5 | 2.7 × 10−4 |
mmu-miR-141-3p | 4.8 | 7.4 × 10 −8 | mmu-miR-582-5p | − 3.1 | 2.8 × 10−4 |
RJ423ba429 vs. RJ423EV | |||||
mmu-miR-204-5p | 10.4 | 1.5 × 10−73 | mmu-miR-346-5p | − 11.9 | 7.6 × 10−59 |
mmu-miR-196a-5p | 7.5 | 1.7 × 10−71 | mmu-miR-199b-5p | − 5.7 | 6.2 × 10−40 |
mmu-miR-200b-3p | 9.2 | 1.2 × 10 −55 | mmu-miR-9-5p | − 4.4 | 3.1 × 10−39 |
mmu-miR-200a-5p | 8.5 | 2.5 × 10 −54 | mmu-miR-330-5p | − 4.3 | 5.3 × 10−39 |
mmu-miR-200b-5p | 8.6 | 9.4 × 10 −30 | mmu-miR-1983 | − 2.9 | 1.2 × 10−34 |
mmu-miR-196a-1-3p | 8.9 | 9.3 × 10−28 | mmu-miR-199a3p | − 2.4 | 4.6 × 10−33 |
mmu-miR-211-5p | 7.0 | 3.8 × 10 21 | mmu-miR-199b-3p | − 2.4 | 1.4 × 10−19 |
mmu-miR-200a-3p | 8.9 | 2.1 × 10 −19 | mmu-miR-146a-5p | − 3.3 | 4.5 × 10−18 |
mmu-miR-204-3p | 9.5 | 3.3 × 10−19 | mmu-miR-138-5p | − 3.8 | 1.3 × 10−17 |
mmu-miR-429-3p | 9.7 | 3.6 × 10 −18 | mmu-miR-9-3p | − 3.9 | 9.9 × 10−17 |