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Table 1 Top 10 upregulated and downregulated miRNAs as determined by miRNA-seq

From: Re-expression of miR-200s in claudin‐low mammary tumor cells alters cell shape and reduces proliferation and invasion potentially through modulating other miRNAs and SUZ12 regulated genes

Upregulated miRNAs log2FC p-value Downregulated miRNAs log2FC p-value
MDA-231c141 vs. MDA-231EV
 hsa-miR-200c-3p 7.1 0 hsa-miR-335-3p − 12.2 0
 hsa-miR-129-5p 3.8 3.1 × 10−65 hsa-miR-452-5p − 9.5 0
 hsa-miR-141-3p 5.3 1.5 × 10 −58 hsa-miR-34c-5p − 3.9 1.4 × 10−136
 hsa-miR-139-5p 2.2 5.4 × 10−50 hsa-miR-34a-5p − 3.8 1.1 × 10−67
 hsa-miR-1301-3p 2.6 3.4 × 10−47 hsa-miR-210-3p − 2.8 4.1 × 10−63
 hsa-miR-30a-5p 1.6 6.0 × 10−46 hsa-miR-335-5p − 7.9 1.1 × 10−59
 hsa-miR-194-5p 2.2 1.3 × 10−45 hsa-miR-27b-5p − 2.4 9.0 × 10−58
 hsa-miR-192-5p 2.3 7.8 × 10−43 hsa-miR-23b-3p − 1.7 2.6 × 10−43
 hsa-miR-455-5p 1.8 1.3 × 10−40 hsa-miR-34b-3p − 4.4 1.4 × 10−41
 hsa-miR-7156-5p 5.2 2.1 × 10−35 hsa-miR-10399-3p − 2.5 2.1 × 10−39
MDA-231ba429 vs. MD-231EV
 hsa-miR-200b-3p 2.9 3.7 × 10 −71 hsa-miR-27b-3p − 1.7 7.6 × 10−59
 hsa-miR-200a-3p 3.2 4.1 × 10 −48 hsa-miR-1269b − 8.7 6.2 × 10−40
 hsa-miR-200a-5p 3.2 2.3 × 10 −32 hsa-miR-3681-5p − 3.9 3.1 × 10−39
 hsa-miR-200b-5p 2.9 1.1 × 10 −26 hsa-miR-34a-5p − 3.5 5.3 × 10−39
 hsa-miR-30c-2-3p 1.1 2.0 × 10−17 hsa-miR-27b-5p − 2.1 1.2 × 10−34
 hsa-miR-708-5p 4.8 9.1 × 10−17 hsa-miR-125b-2-3p − 6.1 4.6 × 10−33
 hsa-miR-218-5p 1.2 4.2 × 10−14 hsa-miR-196a-5p − 3.5 1.4 × 10−19
 hsa-miR-449c-5p 1.8 1.6 × 10−13 hsa-miR-95-3p − 2.5 4.5 × 10−18
 hsa-miR-3074-5p 1.6 1.1 × 10−11 hsa-miR-516a-5p − 4.0 1.3 × 10−17
 hsa-mir-429 1.7 3.6 × 10 −11 hsa-miR-23b-3p − 1.4 9.9 × 10−17
RJ423c141 vs. RJ423EV
 mmu-miR-200c-3p 5.9 3.9 × 10 −51 mmu-miR-365-5p − 8.3 3.4 × 10−13
 mmu-miR-615-3p 8.0 5.0 × 10−43 mmu-miR-132-3p − 3.1 6.5 × 10−12
 mmu-miR-146b-5p 2.5 4.9 × 10−13 mmu-miR-212-5p − 4.0 7.3 × 10−10
 mmu-miR-99a-5p 2.1 4.1 × 10−12 mmu-miR-1983 − 1.9 6.9 × 10−9
 mmu-miR-378c 2.6 7.6 × 10−12 mmu-miR-6540-5p − 8.0 1.2 × 10−7
 mmu-miR-378d 2.4 7.6 × 10−12 mmu-miR-212-3p − 4.7 4.2 × 10−6
 mmu-miR-378a-3p 2.3 2.1 × 10−11 mmu-miR-210-3p − 1.3 5.4 × 10−5
 mmu-miR-125b-2-3p 1.9 7.1 × 10−9 mmu-miR-124-3p − 3.0 2.3 × 10−4
 mmu-miR-141-5p 5.9 2.5 × 10 −8 mmu-miR-582-3p − 2.5 2.7 × 10−4
 mmu-miR-141-3p 4.8 7.4 × 10 −8 mmu-miR-582-5p − 3.1 2.8 × 10−4
RJ423ba429 vs. RJ423EV
 mmu-miR-204-5p 10.4 1.5 × 10−73 mmu-miR-346-5p − 11.9 7.6 × 10−59
 mmu-miR-196a-5p 7.5 1.7 × 10−71 mmu-miR-199b-5p − 5.7 6.2 × 10−40
 mmu-miR-200b-3p 9.2 1.2 × 10 −55 mmu-miR-9-5p − 4.4 3.1 × 10−39
 mmu-miR-200a-5p 8.5 2.5 × 10 −54 mmu-miR-330-5p − 4.3 5.3 × 10−39
 mmu-miR-200b-5p 8.6 9.4 × 10 −30 mmu-miR-1983 − 2.9 1.2 × 10−34
 mmu-miR-196a-1-3p 8.9 9.3 × 10−28 mmu-miR-199a3p − 2.4 4.6 × 10−33
 mmu-miR-211-5p 7.0 3.8 × 10 21 mmu-miR-199b-3p − 2.4 1.4 × 10−19
 mmu-miR-200a-3p 8.9 2.1 × 10 −19 mmu-miR-146a-5p − 3.3 4.5 × 10−18
 mmu-miR-204-3p 9.5 3.3 × 10−19 mmu-miR-138-5p − 3.8 1.3 × 10−17
 mmu-miR-429-3p 9.7 3.6 × 10 −18 mmu-miR-9-3p − 3.9 9.9 × 10−17