Fig. 2

Expression profiles of DEGs and DEMs. a–c Heat map and volcano map of DEG expression levels in the a GSE65626 dataset, b GSE116520 dataset and c GSE116520 dataset. d Venn diagram showing DEGs in the three datasets. e Venn diagram showing DEMs in the two microRNA datasets. The red nodes represent upregulated DEGs with FDR < 0.01 and logFC > 1 or > 1.5; the green nodes represent downregulated DEGs with FDR < 0.01 and logFC < − 1.0 or < − 1.5. DEGs differentially expressed genes. DEMs differentially expressed microRNAs