Fig. 4
From: circ-ANXA7 facilitates lung adenocarcinoma progression via miR-331/LAD1 axis
circ-ANXA7 could directly target the expression of miR-331. a A schematic diagram showing the putative binding sites between circ-ANXA7 and miR-331. b MiRNA microarray expression profiles identified down-regulated miR-331 between LUAD tumor tissues and non-tumor tissues, which was verified by RT-qPCR. c Down-regulated miR-331 was determined in LUAD cells compared to controls by RT-qPCR. d RT-qPCR was utilized to examine miR-331 expression in A549 cells under transfection of pcDNA3.1-circ-ANXA7 and/or miR-331 mimics. e miR-331 expression was determined in A549 cells transfected with sh-circ-ANXA7 and/or miR-331 inhibitor. f Dual luciferase report between circ-ANXA7 and miR-331. g Correlation between circ-ANXA7 and miR-331. **p < 0.01