Fig. 9

Evaluation of the 7-IRG signature in indicating immunotherapeutic benefit in HCC patients. a The different levels of 4 immune checkpoint molecules of HCC tissue among risk groups. b The correlations between 7-IRG signature and the 4 immune checkpoint molecules. Red, positive; Blue, negative. The relationships between the immune-related risk signature and PD1 expression. c CACYBP; d RAET1E; e S100A8. f–h The relationships between the immune-related risk signature and CTLA4 expression. f BIRC5; g SPP1; h S100A8. The correlation was performed by using Pearson correlation analysis. i The distribution of immunotherapeutic response between risk groups in HCC patients. j The difference in risk score between non-responders and responders. k ROC curves for 7-IRG in predicting the immunotherapy response