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Fig. 5 | Cancer Cell International

Fig. 5

From: Loss of PR55α promotes proliferation and metastasis by activating MAPK/AKT signaling in hepatocellular carcinoma

Fig. 5

Knockdown of PR55α by shRNA activates AKT and ERK1/2 signaling. a Microarray analysis was conducted to screen the mRNAs which were subjected to PR55α regulation. b KEGG pathway analysis revealed the potential signaling pathways involved in PR55α. c AKT/ERK signaling pathway protein expressions in HCC cells transfected with shPR55α or shControl were evaluated using western blot. d The indicated proteins of AKT/ERK signaling pathway were detected with or without AKT inhibitor LY294002 (20 μM) and MEK inhibitor U0126 (15 μM)

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Cancer Cell International

ISSN: 1475-2867

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