Fig. 3
From: The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers
The role of IGF2BP2 in regulating multiple human cancer parameters. IGF2BP2 regulates proliferation, apoptosis, cell cycle, migration, invasion, cell viability, MDV, EMT, glycolysis, autophagy, self-renewal, tumor growth etc., of multiple cancer types such AML, breast cancer, colorectal cancer, ERMS, glioma, hepatocellular carcinoma, lung cancer, pancreatic cancer and GBC. IGF2BP2 performs its modulatory functions by interacting with miRNAs, lncRNAs, mRNAs and other m6A-related genes