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Fig. 4 | Cancer Cell International

Fig. 4

From: Prognostic and predictive value of FCER1G in glioma outcomes and response to immunotherapy

Fig. 4

FCER1G is associated with immune infiltration and immune activation in gliomas. a Heatmap showing FCER1G-associated relative abundance of 28 immune cells in gliomas, annotations show corresponding clinical features of each sample. b The correlation between the ssGSEA scores of 28 immune cells and the expression of FCER1G in gliomas. c STRING database shows the PPI network of FCER1G. d Volcano plot of the DEGs expression between FCER1G high and FCER1G low. Cut-off criteria for DEGs significance was adj. p value < 0.05 and the absolute value of the log2 fold change > 1.5. The Y-axis displays the -log10 P-value for each gene, while the X-axis displays the log2 fold change for that gene relative to FCER1G expression. e GO results for differential expression genes. The X-axis represents gene ratio and the Y-axis represents different enriched pathways (BP: biological progress; CC cellular component, MF molecular function). f Rank-based gene set enrichment analysis shows significantly activated immune related pathways in FCER1G high subgroup compared with FCER1G low (LFC, log fold change)

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