Fig. 3

Downregulation of LINC00958 suppresses TSCC tumor growth in vivo. a Nude mice were transplanted subcutaneously with CAL-27 and SCC-9 cells stably transfected with sh-LINC00958 or the control shRNA. A representative picture of the morphology of tumor xenografts after excision at 30 days of treatment. b Tumor volumes were measured every 4 days. c Tumor weights were measured after the mice were sacrificed. d The expression of Ki67 and PCNA in the xenografts were examined by IHC. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001