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Fig. 5 | Cancer Cell International

Fig. 5

From: LINC00958 promotes the proliferation of TSCC via miR-211-5p/CENPK axis and activating the JAK/STAT3 signaling pathway

Fig. 5

MiR-211-5p binds to CENPK and represses its expression. a The overlapping mRNAs from the online analysis tools miRcode (http://www.mircode.org/) and TCGA database. b RT-qPCR of potential target mRNAs of miR-211-5p in CAL-27 cells transfected with miR-211-5p mimics or miR-211-5p inhibitor. c Schematic diagram of the predicted binding sites between CENPK and miR-211-5p. d Luciferase activities in CAL-27 cells co-transfected wild-type (WT) or mutant CENPK plasmid together with miR-211-5p mimic or miR-Ctrl. e Correlation between CENPK and miR-211-5p expression in TSCC tissues based on the TCGA analysis. f Correlation between CENPK and miR-211-5p expression in TSCC clinical samples. g Relative protein level of CENPK in CAL-27 and SCC-9 cells transfected with miR-211-5p mimics, miR-211-5p inhibitor and their corresponding controls. *P < 0.05, **P < 0.01, ***P < 0.001

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